Metabolic disorders

Niemann-Pick Disease: Understanding Symptoms & Treatment

Niemann-Pick Disease is a lipid-storage disorder marked by the excessive accumulation of lipids, including waxes, oils, and cholesterol, in various organs such as the...

Hereditary Hemochromatosis: Understanding Its Impact & Care

Hereditary Hemochromatosis is an inherited iron overload disorder characterized by excessive iron absorption due to hepcidin deficiency. There are four different types of hereditary...

Hypophosphatasia: Understanding A Rare Genetic Disorder

What is Hypophosphatasia? Hypophosphatasia is a rare inborn metabolic disorder that affects the mineralization of bone and teeth. Phosphate is one of the essential minerals necessary...

Biotinidase Deficiency: Understanding the Genetic Disorder

Biotinidase Deficiency is an inherited autosomal recessive disorder in which the enzyme biotinidase is deficient. The enzyme helps to recycle the vitamin biotin, and...

Cachexia: Understanding the Wasting Syndrome & Its Impact

Cachexia, also known as wasting syndrome, is a complicated metabolic syndrome involving muscle mass loss along with anorexia, insulin resistance, and increased protein turnover....

Alkaptonuria: Causes, Symptoms & Treatment Options

What is Alkaptonuria? Alkaptonuria, also known as black urine disease or black bone disease, is a rare hereditary “autosomal recessive” condition stemming from an inborn...